Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | CCR8 | P51685 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117306 | 0.82 | ADORA2A (0.47) | CCR1CCR5CCR8ADORA2AADORA2B | |
| SCHEMBL30506328 | 0.74 | HSD17B10 (0.43) | CCR1CCR5CCR8ADORA2AADORA2B | |
| SCHEMBL17674371 | 0.74 | HSD17B10 (0.43) | CCR1CCR5CCR8ADORA2AADORA2B | |
| SCHEMBL20951908 | 0.72 | PSMD14 (0.43) | KDM4EALDH1A1PSMD14 | |
| SCHEMBL14074978 | 0.68 | SSTR4 (0.38) | CCR1CCR5CCR8ADORA2AKDM4E | |
| SCHEMBL27259309 | 0.67 | ADORA2A (0.42) | CCR1CCR5CCR8ADORA2AADORA2B | |
| SCHEMBL30791898 | 0.66 | HSD17B10 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL20741029 | 0.66 | HSD17B10 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL15342706 | 0.66 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL33526224 | 0.66 | HSD17B10 (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |