Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30968241

O=C(C1C[C@H]2CNC[C@H]2C1)N1N=CCC1c1cc(F)ccc1F.O=C(O)C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 13/20 0.40
NTRK1 P04629 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29455149 1.00 RIPK1 (0.40) RIPK1NTRK1
SCHEMBL22638909 0.94 RIPK1 (0.39) RIPK1
Trifluoroacetic Acid SCHEMBL30968252 0.84 RIPK1 (0.52) RIPK1
Trifluoroacetic Acid SCHEMBL22638918 0.84 RIPK1 (0.52) RIPK1
SCHEMBL28678669 0.82 RIPK1 (0.40) RIPK1
SCHEMBL28673502 0.82 RIPK1 (0.40) RIPK1
SCHEMBL24714794 0.81 RIPK1 (0.43) RIPK1NTRK1
Trifluoroacetic Acid SCHEMBL30968246 0.81 RIPK1 (0.43) RIPK1
SCHEMBL30968268 0.81 RIPK1 (0.37) RIPK1NTRK1
SCHEMBL22638855 0.80 RIPK1 (0.39) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113767092-B Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine 劲方医药科技(上海)有限公司 2024-07-16 CN disclosed