Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.50 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2177775 | 1.00 | CHRNA7 (0.50) | CHRNA7CHRNA10CHRNA9BCHEGRIN1 | |
| SCHEMBL4399009 | 0.98 | BCHE (0.52) | CHRNA7CHRNA10CHRNA9BCHEGRIN1 | |
| Iodide SCHEMBL26093412 | 0.96 | CHRNA7 (0.50) | CHRNA7CHRNA10CHRNA9BCHEGRIN1 | |
| Iodide SCHEMBL26093408 | 0.96 | CHRNA7 (0.50) | CHRNA7CHRNA10CHRNA9BCHEGRIN1 | |
| Hydrochloric Acid SCHEMBL26091078 | 0.96 | CHRNA7 (0.50) | CHRNA7CHRNA10CHRNA9BCHEGRIN1 | |
| Hydrochloric Acid SCHEMBL3313461 | 0.87 | CHRNA7 (0.44) | CHRNA7CHRNA10CHRNA9BCHEGRIN1 | |
| Hydrochloric Acid SCHEMBL2177070 | 0.79 | ACHE (0.53) | BCHEGRIN1GRIN2AACHE | |
| SCHEMBL4399002 | 0.77 | ACHE (0.55) | BCHEGRIN1GRIN2AACHE | |
| Hydrochloric Acid SCHEMBL2176293 | 0.76 | BCHE (0.49) | BCHEGRIN1GRIN2AACHE | |
| Water SCHEMBL31247957 | 0.75 | CHRNA7 (0.67) | CHRNA7CHRNA10CHRNA9BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475559-A | Compounds for malaria treatment | 加泰罗尼亚生物工程基金会研究所 | 2024-08-09 | — | — | CN | disclosed |