Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.51 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.51 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL26093412 | 0.98 | CHRNA7 (0.50) | BCHECHRNA7CHRNA10CHRNA9GRIN1 | |
| Hydrochloric Acid SCHEMBL2177775 | 0.98 | CHRNA7 (0.50) | BCHECHRNA7CHRNA10CHRNA9GRIN1 | |
| Hydrochloric Acid SCHEMBL30968372 | 0.98 | CHRNA7 (0.50) | BCHECHRNA7CHRNA10CHRNA9GRIN1 | |
| Hydrochloric Acid SCHEMBL26091078 | 0.98 | CHRNA7 (0.50) | BCHECHRNA7CHRNA10CHRNA9GRIN1 | |
| Iodide SCHEMBL26093408 | 0.98 | CHRNA7 (0.50) | BCHECHRNA7CHRNA10CHRNA9GRIN1 | |
| Hydrochloric Acid SCHEMBL3313461 | 0.86 | CHRNA7 (0.44) | BCHECHRNA7CHRNA10CHRNA9GRIN1 | |
| SCHEMBL4399002 | 0.79 | ACHE (0.55) | BCHEGRIN1GRIN2AACHEHTT | |
| Hydrochloric Acid SCHEMBL2177070 | 0.77 | ACHE (0.53) | BCHEGRIN1GRIN2AACHEHTT | |
| Water SCHEMBL31247957 | 0.77 | CHRNA7 (0.67) | BCHECHRNA7CHRNA10CHRNA9ACHE | |
| SCHEMBL12533275 | 0.77 | CHRNA7 (0.67) | BCHECHRNA7CHRNA10CHRNA9ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178678-B2 | Bis-quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178678-B2 | Bis-quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-03-18 | — | — | US | disclosed |
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | CHRNA2, CHRNA5, CHRNA4 | BCHE 39/4885CHRNA7 7/4885CHRNA10 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.