Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722748 | 1.00 | KDM4E (0.35) | KDM4EL3MBTL1MAPTRAB9AGLA | |
| SCHEMBL21474580 | 0.74 | SLC6A3 (0.44) | KDM4EL3MBTL1MAPTRAB9ASLC6A3 | |
| SCHEMBL27617877 | 0.70 | ALDH1A1 (0.56) | KDM4EL3MBTL1MAPTRAB9AGLA | |
| SCHEMBL12389716 | 0.70 | CA12 (0.47) | KDM4EL3MBTL1MAPTRAB9AGLA | |
| SCHEMBL20136606 | 0.67 | SLC6A3 (0.42) | MAPTRAB9AGAASLC6A3SLC6A2 | |
| SCHEMBL16798334 | 0.67 | CASP1 (0.41) | — | |
| SCHEMBL30415198 | 0.67 | CASP1 (0.41) | — | |
| SCHEMBL24773853 | 0.66 | CA12 (0.49) | KDM4EL3MBTL1MAPTGAATDP1 | |
| SCHEMBL22321497 | 0.66 | CA12 (0.49) | KDM4EL3MBTL1GLAGAATDP1 | |
| SCHEMBL31387952 | 0.66 | CA12 (0.49) | KDM4EL3MBTL1MAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |