Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190528 | 0.91 | ALDH1A1 (0.55) | ALDH1A1CCNB2CDK1CCNB1CDK5 | |
| Quinoxaline SCHEMBL27830916 | 0.91 | ALDH1A1 (0.55) | ALDH1A1CCNB2CDK1CCNB1CDK5 | |
| Quinoxaline SCHEMBL28165605 | 0.90 | NOTUM (0.71) | ALDH1A1NOTUMCCNB2CDK1CCNB1 | |
| Quinoxaline SCHEMBL27549902 | 0.88 | ALDH1A1 (0.52) | ALDH1A1CCNB2CDK1CCNB1CDK5 | |
| Quinoxaline SCHEMBL5315 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CCNB2CDK1CCNB1CDK5 | |
| Quinoxaline SCHEMBL30320908 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CCNB2CDK1CCNB1CDK5 | |
| Quinoxaline SCHEMBL6928518 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CCNB2CDK1CCNB1CDK5 | |
| Quinoxaline SCHEMBL29355228 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CCNB2CDK1CCNB1CDK5 | |
| Biphenyl SCHEMBL28549078 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NOTUMNPC1RAB9ANFKB1 | |
| Biphenyl SCHEMBL29127776 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NOTUMNPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480146-A | Preparation method of polyprenol-based light-controlled antibacterial synergist | 中国林业科学研究院林产化学工业研究所 | 2024-08-13 | — | — | CN | claimed |
| CN-1352809-A | Conductive polymers | QINITIK CO LTD (GB) | 2002-06-05 | — | — | CN | claimed |
| CN-118480146-A | Preparation method of polyprenol-based light-controlled antibacterial synergist | 中国林业科学研究院林产化学工业研究所 | 2024-08-13 | — | — | CN | disclosed |
| CN-115028624-B | Quinoxaline skeleton NN oxazoline ligand and synthetic method and application thereof | 上海师范大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-113045506-A | Triphenylamine quinoxaline malononitrile, synthetic method thereof and method for detecting CN < - > | 阜阳师范大学 | 2021-06-29 | — | — | CN | disclosed |
| EP-2694067-B1 | PYRIDOPYRAZINE DERIVATIVES AND THEIR USE | TERNA ZENTARIS GMBH (DE) | 2015-08-26 | — | — | EP | disclosed |
| CN-103080114-B | Benzene azole dithiophene organic semiconductor material and preparation method and application thereof | OCEANS KING LIGHTING SCIENCE | 2015-05-06 | — | — | CN | disclosed |
| US-8937068-B2 | Pyridopyrazine derivatives and their use | ZENTARIS GMBH (DE) | 2015-01-20 | — | — | US | disclosed |
| US-8912189-B2 | Pyridopyrazine derivatives and their use | AETERNA ZENTARIS GMBH (DE) | 2014-12-16 | — | — | US | disclosed |
| CN-102386330-B | Quinoxaline derivative, and organic semiconductor device, electric field light emitting device, and electronic device which have the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-10-22 | — | — | CN | disclosed |
| US-8791118-B2 | Pyridopyrazines as highly selective ras-Raf-Mek-Erk signal transduction pathway inhibitors | AETERNA ZENTARIS GMBH (DE) | 2014-07-29 | — | — | US | disclosed |
| CN-101215299-A | Quinoxalines ligand iridium complexes and synthetic method thereof | UNIV LIAONING (CN) | 2008-07-09 | — | — | CN | disclosed |
| US-20070123494-A1 | PYRIDOPYRAZINE DERIVATIVES AND THEIR USE | ZENTARIS GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| CN-1795195-A | Novel pyridopyrazines and their use as kinase modulators | ZENTARIS GMBH (DE) | 2006-06-28 | — | — | CN | disclosed |
| CN-1777592-A | Quinoxaline derivative, and organic semiconductor element, electroluminescent element and electronic device using the same | SEMICONDUCTOR ENERGY LAB (JP) | 2006-05-24 | — | — | CN | disclosed |
| CN-1711275-A | Palladium and platinum complexes | COVION ORGANIC SEMICONDUCTORS (DE) | 2005-12-21 | — | — | CN | disclosed |
| CN-1531541-A | Rhodium and iridium complexes | �����л��뵼������˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1352809-A | Conductive polymers | QINITIK CO LTD (GB) | 2002-06-05 | — | — | CN | disclosed |
| CN-1309680-A | heat curable epoxy composition | VANTICO AG (CH) | 2001-08-22 | — | — | CN | disclosed |
| US-4005022-A | PIGMENT-DYE-POLYMER IN AN ALIPHATIC SATURATED HYDROCARBON | PITNEY-BOWES, INC. (US) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123494-A1 | PYRIDOPYRAZINE DERIVATIVES AND THEIR USE | PLPBP, PDXK, MAP4K2 | ALDH1A1 1192/4885NOTUM 3876/4885CCNB2 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.