Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.46 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 2/20 | 0.43 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278687 | 1.00 | PKM (0.49) | PKMDHODHKDM4EL3MBTL1RAB9A | |
| SCHEMBL20509746 | 0.83 | HTT (0.49) | PKMDHODHKDM4ERAB9ASPR | |
| SCHEMBL30968893 | 0.83 | KDM4E (0.47) | PKMDHODHKDM4EL3MBTL1RAB9A | |
| SCHEMBL1901177 | 0.77 | PKM (0.46) | PKMDHODHKDM4ERAB9ASPR | |
| SCHEMBL4904903 | 0.75 | PKM (0.45) | PKMDHODHRAB9ASPRCAMKK1 | |
| SCHEMBL9525340 | 0.75 | HAVCR2 (0.48) | PKMDHODHKDM4EL3MBTL1KDM4A | |
| SCHEMBL9754157 | 0.74 | KDM4E (0.48) | PKMDHODHKDM4EL3MBTL1RAB9A | |
| SCHEMBL20509551 | 0.73 | KDM4E (0.37) | PKMKDM4ERAB9ALMNACYP1A2 | |
| SCHEMBL30935918 | 0.72 | ALDH1A1 (0.52) | PKMDHODHKDM4ERAB9AALDH1A1 | |
| SCHEMBL23412562 | 0.72 | KDM4C (0.42) | PKMKDM4EL3MBTL1RAB9AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118059093-A | Inhibitors of short chain dehydrogenase activity for the treatment of fibrosis | 卡斯西部储备大学 | 2024-05-24 | — | — | CN | disclosed |