Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968889 | 0.83 | PKM (0.49) | KDM4EL3MBTL1ALDH1A1MAPTLIMK1 | |
| SCHEMBL11278687 | 0.83 | PKM (0.49) | KDM4EL3MBTL1ALDH1A1MAPTLIMK1 | |
| SCHEMBL20509746 | 0.81 | HTT (0.49) | KDM4EALDH1A1MAPK1LIMK1CHEK1 | |
| SCHEMBL4892703 | 0.76 | MEN1 (0.41) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL27788768 | 0.75 | LIMK1 (0.51) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL1497897 | 0.73 | MEN1 (0.44) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL20509551 | 0.71 | KDM4E (0.37) | KDM4EMEN1ALDH1A1KMT2ALIMK1 | |
| Hydrochloric Acid SCHEMBL6196266 | 0.71 | MEN1 (0.43) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4157610 | 0.70 | CHEK1 (0.45) | L3MBTL1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22270837 | 0.70 | CHEK1 (0.45) | L3MBTL1MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118059093-A | Inhibitors of short chain dehydrogenase activity for the treatment of fibrosis | 卡斯西部储备大学 | 2024-05-24 | — | — | CN | disclosed |