Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 7/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6196266 | 0.98 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL1150804 | 0.85 | KDR (0.42) | MEN1KMT2AKDRPARP1PDPK1 | |
| SCHEMBL11277616 | 0.84 | KDR (0.44) | MEN1KMT2AKDM4EKDRPARP1 | |
| SCHEMBL25201385 | 0.84 | KDR (0.41) | MEN1KMT2AKDRPARP1PDPK1 | |
| SCHEMBL954193 | 0.82 | AXL (0.38) | MEN1KMT2AKDRPARP1PDPK1 | |
| SCHEMBL10650329 | 0.82 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EKDR | |
| SCHEMBL25191211 | 0.78 | KDR (0.38) | ALDH1A1KDRPARP1PDPK1AXL | |
| SCHEMBL17440429 | 0.78 | KDR (0.45) | MEN1KMT2AALDH1A1KDM4EKDR | |
| SCHEMBL24322141 | 0.75 | AXL (0.38) | MEN1KMT2AALDH1A1KDRPARP1 | |
| SCHEMBL3977601 | 0.75 | AXL (0.42) | MEN1KMT2AALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003980-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | Ribon Therapeutics Inc. (US) | 2022-06-01 | — | — | EP | claimed |
| US-7897614-B2 | Preventive agent/remedial agent for constipation predominant IBS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-03-01 | — | — | US | claimed |
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | claimed |
| EP-1829543-B1 | Preventive agent/remedial agent for constipation predominant IBS | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-01-21 | — | — | EP | claimed |
| EP-1829543-A1 | Preventive agent/remedial agent for constipation predominant IBS | MITSUBISHI PHARMA CORPORATION (JP) | 2007-09-05 | — | — | EP | claimed |
| EP-1419772-B1 | PREVENTIVE AGENT/REMEDIAL AGENT FOR CONSTIPATION PREDOMINANT IBS | MITSUBISHI PHARMA CORP (JP) | 2007-07-25 | — | — | EP | claimed |
| EP-1256581-B1 | PREVENTIVE OR THERAPEUTIC AGENTS FOR GASTRIC OR ESOPHAGEAL REGURGITATION | MITSUBISHI PHARMA CORP (JP) | 2007-03-28 | — | — | EP | claimed |
| US-20070004770-A1 | Preventive agent/remedial agent for constipation predominant IBS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-04 | — | — | US | claimed |
| US-20060281781-A1 | Preventive and therapeutic medicament for gastroesophageal reflux disease | EDUSA PHARMACEUTICALS, INC. | 2006-12-14 | — | — | US | claimed |
| US-20050282852-A1 | Preventive and therapeutic medicament for gastroesophageal reflux disease | YAMAZAKI SATOSHI | 2005-12-22 | — | — | US | claimed |
| US-6967207-B2 | Preventive or therapeutic agents for gastric or esophageal regurgitation | MITSUBISHI PHARMA CORPORATION (JP) | 2005-11-22 | — | — | US | claimed |
| US-20040248927-A1 | Preventive agent/remedial agent for constipation predominant ibs | MITSUBISHI PHARMA CORPORATION (JP) | 2004-12-09 | — | — | US | claimed |
| EP-1419772-A1 | PREVENTIVE AGENT/REMEDIAL AGENT FOR CONSTIPATION PREDOMINANT IBS | Mitsubishi Pharma Corporation (JP) | 2004-05-19 | — | — | EP | claimed |
| US-20030130304-A1 | Preventive or therapeutic agents for gastric or esophageal regurgitation | MITSUBISHI PHARMA CORPORATION (JP) | 2003-07-10 | — | — | US | claimed |
| EP-1256581-A1 | PREVENTIVE OR THERAPEUTIC AGENTS FOR GASTRIC OR ESOPHAGEAL REGURGITATION | Mitsubishi Pharma Corporation (JP) | 2002-11-13 | — | — | EP | claimed |
| EP-4003980-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | Ribon Therapeutics Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| US-7897614-B2 | Preventive agent/remedial agent for constipation predominant IBS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20030130304-A1 | Preventive or therapeutic agents for gastric or esophageal regurgitation | MITSUBISHI PHARMA CORPORATION (JP) | 2003-07-10 | — | — | US | disclosed |
| WO-2003018012-A1 | PREVENTIVE AGENT/REMEDIAL AGENT FOR CONSTIPATION PREDOMINANT IBS | MITSUBISHI PHARMA CORPORATION (JP) | 2003-03-06 | — | — | WO | disclosed |
| EP-1256581-A1 | PREVENTIVE OR THERAPEUTIC AGENTS FOR GASTRIC OR ESOPHAGEAL REGURGITATION | Mitsubishi Pharma Corporation (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248927-A1 | Preventive agent/remedial agent for constipation predominant ibs | BRS3, SLC10A2, FABP2 | MEN1 4250/4885KMT2A 2702/4885ALDH1A1 1982/4885 |
| US-20070004770-A1 | Preventive agent/remedial agent for constipation predominant IBS | SLC10A2, FABP2, SI | MEN1 4336/4885KMT2A 2122/4885ALDH1A1 804/4885 |
| US-20050282852-A1 | Preventive and therapeutic medicament for gastroesophageal reflux disease | HRH2, SLC10A2, GRPR | MEN1 3574/4885KMT2A 3483/4885ALDH1A1 112/4885 |
| US-20060281781-A1 | Preventive and therapeutic medicament for gastroesophageal reflux disease | HRH2, SLC10A2, GRPR | MEN1 3574/4885KMT2A 3483/4885ALDH1A1 112/4885 |
| US-20030130304-A1 | Preventive or therapeutic agents for gastric or esophageal regurgitation | HRH2, SLC10A2, ABCB11 | MEN1 3563/4885KMT2A 4221/4885ALDH1A1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.