Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 7/20 | 0.39 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411815 | 0.80 | HPGDS (0.36) | CHRNA7CHRNA10CHRNA9HPGDSCCNC | |
| SCHEMBL15950956 | 0.77 | CCNC (0.56) | CHRNA7CHRNA10CHRNA9HPGDSPIM1 | |
| SCHEMBL11983532 | 0.69 | PIM1 (0.69) | PIM1LRRK2MAPK1KDM4EALDH1A1 | |
| SCHEMBL28848228 | 0.68 | CHRNA7 (0.35) | CHRNA7CHRNA10CHRNA9HPGDS | |
| SCHEMBL25251073 | 0.68 | LRRK2 (0.43) | PIM1LRRK2ROCK2ROCK1CDC42BPB | |
| SCHEMBL29404187 | 0.68 | PIK3CD (0.52) | PIM1LRRK2MAPK1PIK3CDPIK3CA | |
| SCHEMBL28320605 | 0.67 | LTA4H (0.62) | CHRNA7CHRNA10CHRNA9HPGDSCCNC | |
| Benzene SCHEMBL27662532 | 0.66 | PIK3CD (0.44) | PIM1LRRK2MAPK1KDM4EALDH1A1 | |
| SCHEMBL18487593 | 0.66 | L3MBTL1 (0.65) | PIM1LRRK2ATRKDM4EALDH1A1 | |
| SCHEMBL30635496 | 0.66 | PIK3CD (0.47) | LRRK2MAPK1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805462-B | Steroid derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-06-18 | — | — | CN | disclosed |