Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.50 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019874 | 0.88 | HCAR3 (0.61) | NMT1HCAR3ACHE | |
| SCHEMBL28914847 | 0.83 | CYP3A4 (0.49) | NMT1HCAR3ACHE | |
| SCHEMBL30969276 | 0.82 | CCNA2 (0.51) | PIM1FLT3PIM3BRSK1AURKB | |
| SCHEMBL4418348 | 0.81 | KDM4E (0.56) | — | |
| SCHEMBL30969300 | 0.80 | SIGMAR1 (0.52) | NMT1PIM1FLT3PIM3BRSK1 | |
| SCHEMBL6154983 | 0.79 | TNIK (0.49) | EPHX2HRH3 | |
| SCHEMBL4069152 | 0.79 | HRH3 (0.62) | NMT1ACHEHRH4HRH3 | |
| SCHEMBL5205802 | 0.78 | NNMT (0.60) | NNMTHCAR3DPP4EPHX2 | |
| SCHEMBL30969317 | 0.77 | TNIK (0.51) | EPHX2 | |
| SCHEMBL30492154 | 0.77 | NNMT (0.58) | NNMTHCAR3DPP4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |