SCHEMBL30969293

SCHEMBL30969293

O=C1CCN(C(=O)CCN2Cc3ccccc3C2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
HPGD P15428 4/20 0.51
MAPT P10636 2/20 0.51
LMNA P02545 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HDAC3 O15379 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC8 Q9BY41 1/20 0.50
NCOR2 Q9Y618 1/20 0.50
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HTR1A P08908 2/20 0.49
HTR7 P34969 2/20 0.49
CHRM2 P08172 2/20 0.48
CHRM4 P08173 2/20 0.48
CHRM1 P11229 2/20 0.48
CHRM3 P20309 2/20 0.48
KDM4E B2RXH2 2/20 0.47
HSD17B10 Q99714 2/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL794685 0.82 HDAC3 (0.72) ALDH1A1HPGDMAPTLMNANPSR1
SCHEMBL22784699 0.77 HDAC3 (0.60) ALDH1A1HPGDMAPTLMNANPSR1
SCHEMBL4698272 0.73 NPC1 (0.73) ALDH1A1HPGDMAPTTSHRSMN1; SMN2
SCHEMBL6986385 0.72 HDAC3 (0.51) ALDH1A1MAPTLMNANPSR1HDAC3
Hydrochloric Acid SCHEMBL6986394 0.72 KDM4E (0.54) ALDH1A1MAPTLMNANPSR1HDAC3
SCHEMBL15224117 0.71 KMT2A (0.44) ALDH1A1HPGDMAPTLMNANPSR1
SCHEMBL19931588 0.71 HDAC3 (0.65) ALDH1A1HPGDMAPTLMNANPSR1
SCHEMBL3477555 0.70 HDAC3 (0.70) ALDH1A1MAPTHDAC3HDAC1HDAC8
SCHEMBL6228768 0.70 HDAC3 (0.68) ALDH1A1HPGDMAPTLMNANPSR1
SCHEMBL5658350 0.70 HTR7 (0.64) ALDH1A1HPGDMAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642766-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-05 EP disclosed
WO-2024145585-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-04 WO disclosed