Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6113984 | 0.83 | GAA (0.62) | PRSS1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3857978 | 0.82 | ALDH1A1 (0.49) | PRSS1PRMT5WDR77THRATHRB | |
| SCHEMBL6807626 | 0.81 | MCHR1 (0.57) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL30969248 | 0.80 | MAPK1 (0.68) | PRSS1THRATHRBCYP1A2CYP3A4 | |
| SCHEMBL6811199 | 0.80 | MAPK1 (0.68) | PRSS1THRATHRBCYP1A2CYP3A4 | |
| SCHEMBL3863330 | 0.79 | ALDH1A1 (0.50) | PRMT5WDR77THRATHRBKDM4E | |
| SCHEMBL2559475 | 0.79 | PRSS1 (0.60) | PRSS1THRATHRBKDM4EALDH1A1 | |
| SCHEMBL6803935 | 0.79 | MCHR1 (0.59) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL6811996 | 0.77 | MCHR1 (0.60) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7040004 | 0.76 | NPC1 (0.68) | KDM4EALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |