Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969248 | 1.00 | MAPK1 (0.68) | MAPK1MCHR1ACHEPRSS1CYP1A2 | |
| SCHEMBL6807626 | 0.85 | MCHR1 (0.57) | MAPK1MCHR1CYP1A2CYP2D6SCN1A | |
| SCHEMBL6811996 | 0.83 | MCHR1 (0.60) | MAPK1MCHR1CYP1A2CYP2D6SCN1A | |
| SCHEMBL5132218 | 0.83 | MAPK1 (0.62) | MAPK1MCHR1PRSS1 | |
| SCHEMBL6803935 | 0.83 | MCHR1 (0.59) | MAPK1MCHR1CYP1A2CYP2D6SCN1A | |
| SCHEMBL8068426 | 0.82 | MAPK1 (0.68) | MAPK1PRSS1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1545264 | 0.82 | MAPK1 (0.68) | MAPK1PRSS1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12970778 | 0.81 | MAPK1 (0.72) | MAPK1PRSS1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6941556 | 0.81 | MAPK1 (0.72) | MAPK1PRSS1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9502719 | 0.81 | MAPK1 (0.72) | MAPK1PRSS1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063686-A1 | Carboxamide compounds and their use as antagonists of a human 11cby receptor | JOHNSON CHRISTOPHER NORBERT (GB) | 2004-04-01 | — | — | US | disclosed |
| EP-1305304-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM PLC (GB) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010146-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063686-A1 | Carboxamide compounds and their use as antagonists of a human 11cby receptor | CNR1, GPR3, CCKAR | MAPK1 1964/4885MCHR1 133/4885ACHE 1228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.