Alpha-Tocopherol

Alpha-Tocopherol

SCHEMBL3097

Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
TTPA P49638 3/20 1.00
MAPT P10636 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
GSTP1 P09211 1/20 1.00
USP2 O75604 1/20 1.00
THRB P10828 1/20 1.00
CYP2C9 P11712 1/20 1.00
CYP2C19 P33261 1/20 1.00
NR1I2 O75469 2/20 0.85
ALOX5 P09917 1/20 0.78
PDE4A P27815 1/20 0.70
PDE3A Q14432 1/20 0.70
GSTO1 P78417 2/20 0.69
PSEN1 P49768 2/20 0.67
PTPN1 P18031 1/20 0.64
AKT1 P31749 4/20 0.58
PDPK1 O15530 1/20 0.58
PHLPP1 O60346 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alpha-Tocopherol SCHEMBL10295722 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
SCHEMBL8084077 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL8408151 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL14297170 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL17874901 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL16451007 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tochopherol SCHEMBL14315133 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL14167439 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL3059188 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL20817063 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 608758 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372755-B1 None US claimed
CN-118344310-A Compound, preparation method, lipid nanoparticle thereof and pharmaceutical composition 苏州慧疗生物医药科技有限公司 2024-07-16 CN claimed
CN-113116891-B Cream and preparation method thereof 重庆华邦制药有限公司 2024-07-16 CN claimed
CN-118318999-A Lipid-lowering composite powder mainly containing linolenic acid and preparation method thereof 河南善恩医药科技有限公司 2024-07-12 CN claimed
CN-118318936-A Functional feed for improving quality of cabin-cultured large yellow croaker 中国海洋大学 2024-07-12 CN claimed
CN-118325622-A Alternaria alternata preparation and preparation method and application thereof 黑龙江省黑土保护利用研究院 2024-07-12 CN claimed
US-20240226005-A1 NANO- AND MICRO-FORMULATIONS HUXLEY HEALTH, INC. (CA) 2024-07-11 US claimed
US-20240226058-A1 STABILIZED CANNABINOID COMPOSITIONS AND METHODS OF PREPARATION THEREOF Cannacraft, Inc. (US) 2024-07-11 US claimed
WO-2024145963-A1 IONIZABLE CATIONIC LIPID COMPOUND AND COMPOSITION FOR DELIVERING NUCLEIC ACID AND USE THEREOF 北京悦康科创医药科技股份有限公司 2024-07-11 WO claimed
US-20240226032-A9 PHARMACEUTICAL COMPOSITION COMPRISING A CANNABINOID JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2024-07-11 US claimed
US-4000322-A BLENDING, HONEY GERBER PRODUCTS COMPANY (US) 1976-12-28 US claimed
US-4000276-A HUMAN SKIN KANEBO, LTD. (JA) 1976-12-28 US claimed
US-3993756-A Antilipemic agent containing a soybean oil fraction KANEDA TAKASHI 1976-11-23 US claimed
US-3962384-A Spray-drying technique for preparing agglomerated powders HOFFMANN-LA ROCHE INC. (US) 1976-06-08 US claimed
US-3957966-A VINYLPYRROLIDONE POLYMER, PLASTICIZER GAF CORPORATION (US) 1976-05-18 US claimed
US-RE28819-E Dialkylated glycol compositions and medicament preparations containing same SYNTEX (U.S.A.) INC. (US) 1976-05-18 US claimed
US-3949067-A Shaving lubricant GIBBS HAROLD E 1976-04-06 US claimed
US-3946109-A THYROXINE, VITAMIN A, E, OR T KOLB ERNST 1976-03-23 US claimed
US-3944550-A Vitamin E orotate and a method of producing the same KANEBO LTD. (JA) 1976-03-16 US claimed
US-3932634-A High potency vitamin water dispersible formulations PFIZER INC. (US) 1976-01-13 US claimed