Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | TTPA | P49638 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | GSTP1 | P09211 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.85 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.78 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.69 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | AKT1 | P31749 | 4/20 | 0.58 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.58 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Tocopherol SCHEMBL14297170 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL14167439 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL13055549 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL10295722 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL8408151 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tochopherol SCHEMBL22303 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL16430896 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL15441194 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL20817063 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tochopherol SCHEMBL14315133 | 1.00 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209132-A1 | COUPLING OF 2,3,5-TRIMETHYLHYDROQUINONE AND UNSATURATED ALCOHOLS | DSM IP ASSETS B.V. (NL) | 2024-06-27 | — | — | US | disclosed |
| US-20100273871-A1 | ANTICANCER TOCOPHERYL SUCCINATE DERIVATIVES | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273871-A1 | ANTICANCER TOCOPHERYL SUCCINATE DERIVATIVES | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-10-28 | — | — | US | disclosed |
| US-7524836-B2 | Nitrooxyderivative steroidal compounds | NICOX S.A. (FR) | 2009-04-28 | — | — | US | disclosed |
| EP-1986635-A4 | ANTICANCER AGENTS | UNIV OHIO STATE RES FOUND (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1986635-A2 | ANTICANCER AGENTS | THE OHIO STATE RESEARCH FOUNDATION (US) | 2008-11-05 | — | — | EP | disclosed |
| US-7378412-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2008-05-27 | — | — | US | disclosed |
| US-20080009545-A1 | Anticancer agents | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-01-10 | — | — | US | disclosed |
| WO-2007098139-A2 | ANTICANCER AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070142342-A1 | Pharmaceutical compounds | NICOX S.A. | 2007-06-21 | — | — | US | disclosed |
| EP-0658552-B1 | Process for the preparation of alpha-tocopherol derivatives | EISAI CO LTD (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5610113-A | REACTION OF TRIMETHYLHYDROQUINONE AND ISOPHYTOL, CONDENSATION AND CYCLIZATION, SCANDIUM SAPONITE CATALYST | EISAI CO., LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5536852-A | ETHERIFICATION, CYCLIZATION | EISAI CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5532387-A | CYCLIZATION OF TRIMETHYLHYDROQUINONE AND AN ALKENYL ALCOHOL, REUSABLE CATALYST, IIIB FLUOROSULFONATE, NITRATE, SULFATE, OR FLUOROALKYLSULFONATE | EISAI CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| CN-1116203-A | Process for the preparation of alpha-tocopherol derivatives, and catalyst | EISAI CO LTD (JP) | 1996-02-07 | — | — | CN | disclosed |
| EP-0677520-A1 | Process for the preparation of alpha-tocopherol derivatives, and catalyst | Eisai Co., Ltd. (JP) | 1995-10-18 | — | — | EP | disclosed |
| CN-1108254-A | Process for the preparation of alpha-tocopherol derivatives | EISAI CO LTD (JP) | 1995-09-13 | — | — | CN | disclosed |
| EP-0658552-A1 | Process for the preparation of alpha-tocopherol derivatives | Eisai Co., Ltd. (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0306904-B1 | PHOSPHORIC ACID DIESTERS AND SALTS THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0306904-A2 | Phosphoric acid diesters and salts thereof | Senju Pharmaceutical Co., Ltd. (JP) | 1989-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142342-A1 | Pharmaceutical compounds | CYP11B2, CYP11B1, CYP2S1 | LMNA 3381/4885TTPA 1068/4885MAPT 3031/4885 |
| US-20100273871-A1 | ANTICANCER TOCOPHERYL SUCCINATE DERIVATIVES | SDHA, SDHB, SUCNR1 | LMNA 1518/4885TTPA 8/4885MAPT 4728/4885 |
| US-20080009545-A1 | Anticancer agents | SUCNR1, CPS1, HIF1AN | LMNA 3247/4885TTPA 3406/4885MAPT 4790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.