Alpha-Tocopherol

Alpha-Tocopherol

SCHEMBL16430896

Cc1c(C)c2c(c(C)c1O)CCC(C)(CCC[C@@H](C)CCC[C@H](C)CCCC(C)C)O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 1.00
▸ TTPA P49638 3/20 1.00
▸ MAPT P10636 2/20 1.00
▸ MEN1 O00255 2/20 1.00
▸ KMT2A Q03164 2/20 1.00
▸ GSTP1 P09211 1/20 1.00
▸ USP2 O75604 1/20 1.00
▸ THRB P10828 1/20 1.00
▸ CYP2C9 P11712 1/20 1.00
▸ CYP2C19 P33261 1/20 1.00
▸ NR1I2 O75469 2/20 0.85
▸ ALOX5 P09917 1/20 0.78
▸ PDE4A P27815 1/20 0.70
▸ PDE3A Q14432 1/20 0.70
▸ GSTO1 P78417 2/20 0.69
▸ PSEN1 P49768 2/20 0.67
▸ PTPN1 P18031 1/20 0.64
▸ AKT1 P31749 4/20 0.58
▸ PDPK1 O15530 1/20 0.58
▸ PHLPP1 O60346 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alpha-Tocopherol SCHEMBL14297170 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL14167439 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL13055549 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
SCHEMBL3109160 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL10295722 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL8408151 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tochopherol SCHEMBL22303 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
SCHEMBL15441194 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL20817063 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tochopherol SCHEMBL14315133 1.00 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023017533-A1 A NUTRITIONAL CAPSULE OF AYURVEDIC HERBS, UNANI HERBS, MINERALS, AMINO ACIDS, VITAMINS, PROBIOTIC AND NUTRACEUTICALS AUFFULLEN HEALTHCARE PVT. LTD. (IN) 2023-02-16 — — WO disclosed
US-20220169834-A1 Method for Improving UV Weatherability of Thermoplastic Vulcanizates CELANESE INTERNATIONAL CORPORATION 2022-06-02 — — US disclosed
US-11246853-B2 Method for evaluating the ability of a composition to prevent muscle damage and fatigue; food supplement and drug SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2022-02-15 — — US disclosed
US-20210338633-A1 METHOD FOR EVALUATING THE ABILITY OF A COMPOSITION TO PREVENT MUSCLE DAMAGE AND FATIGUE; FOOD SUPPLEMENT AND DRUG SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2021-11-04 — — US disclosed
EP-3449252-B1 METHOD FOR EVALUATING THE ABILITY OF A COMPOSITION TO PREVENT MUSCLE DAMAGE AND FATIGUE SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2020-05-06 — — EP disclosed
US-20190160042-A1 METHOD FOR EVALUATING THE ABILITY OF A COMPOSITION TO PREVENT MUSCLE DAMAGE AND FATIGUE; FOOD SUPPLEMENT AND DRUG SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2019-05-30 — — US disclosed
EP-3027170-B1 NOVEL USES OF ALKYLPOLYGLYCOSIDES FOR SOLUBILISING VITAMIN E IN WATER, CORRESPONDING COMPOSITIONS SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2018-04-25 — — EP disclosed
WO-2017187033-A1 METHOD FOR EVALUATING THE ABILITY OF A COMPOSITION TO PREVENT MUSCLE DAMAGE AND FATIGUE; FOOD SUPPLEMENT AND DRUG SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2017-11-02 — — WO disclosed
US-20160193340-A1 NOVEL USES OF ALKYL POLYGLYCOSIDES FOR SOLUBILISING VITAMIN E IN WATER; COMPOSITIONS COMPRISING SAME SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2016-07-07 — — US disclosed
EP-3027170-A1 NOVEL USES OF ALKYL POLYGLYCOSIDES FOR SOLUBILISING VITAMIN E IN WATER; COMPOSITIONS COMPRISING SAME Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2016-06-08 — — EP disclosed
WO-2015015092-A1 NOVEL USES OF ALKYL POLYGLYCOSIDES FOR SOLUBILISING VITAMIN E IN WATER; COMPOSITIONS COMPRISING SAME SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2015-02-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190160042-A1 METHOD FOR EVALUATING THE ABILITY OF A COMPOSITION TO PREVENT MUSCLE DAMAGE AND FATIGUE; FOOD SUPPLEMENT AND DRUG GYS1, PYGM, MYOF LMNA 1680/4885TTPA 14/4885MAPT 4019/4885
US-11246853-B2 Method for evaluating the ability of a composition to prevent muscle damage and fatigue; food supplement and drug GYS1, PYGM, MYOF LMNA 1680/4885TTPA 14/4885MAPT 4019/4885
US-20210338633-A1 METHOD FOR EVALUATING THE ABILITY OF A COMPOSITION TO PREVENT MUSCLE DAMAGE AND FATIGUE; FOOD SUPPLEMENT AND DRUG PYGM, TNNC1, GYS1 LMNA 369/4885TTPA 89/4885MAPT 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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