Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970483 | 0.88 | CCNA2 (0.34) | F2CNR1 | |
| SCHEMBL30970487 | 0.88 | CCNA2 (0.34) | F2CNR1 | |
| SCHEMBL25215919 | 0.81 | F2 (0.38) | F2ALDH1A1GAACYP19A1MAPT | |
| SCHEMBL30970492 | 0.80 | AKR1C3 (0.34) | F2ALDH1A1GAACYP19A1MAPT | |
| SCHEMBL30368421 | 0.78 | HSP90AA1 (0.40) | CNR1 | |
| SCHEMBL25600347 | 0.77 | MAPT (0.34) | F2ALDH1A1GAACYP19A1MAPT | |
| SCHEMBL30368441 | 0.75 | QRFPR (0.42) | ALDH1A1NPSR1CNR1HTT | |
| SCHEMBL30970490 | 0.74 | TRAP1 (0.33) | GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL30301766 | 0.74 | TRAP1 (0.37) | ALDH1A1MEN1KMT2ATHRBL3MBTL1 | |
| SCHEMBL30301748 | 0.74 | TRAP1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317949-A | Isoindolines as PMS2 inhibitors | 奈奥芬莱有限公司 | 2024-07-09 | — | — | CN | disclosed |