Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970483 | 1.00 | CCNA2 (0.34) | CCNA2CDK2CDK1CCNB1CNR1 | |
| SCHEMBL30970495 | 0.88 | F2 (0.35) | CNR1F2 | |
| SCHEMBL30970490 | 0.86 | TRAP1 (0.33) | — | |
| SCHEMBL30970485 | 0.85 | HSP90AA1 (0.33) | — | |
| SCHEMBL30970486 | 0.85 | HSP90AA1 (0.33) | — | |
| SCHEMBL30368421 | 0.80 | HSP90AA1 (0.40) | CNR1 | |
| SCHEMBL25210256 | 0.80 | TRAP1 (0.36) | CCNA2CDK2CDK1CCNB1FABP4 | |
| SCHEMBL30377318 | 0.80 | TRAP1 (0.36) | CCNA2CDK2CDK1CCNB1FABP4 | |
| SCHEMBL25212540 | 0.79 | F2 (0.36) | F2 | |
| SCHEMBL31281890 | 0.79 | TRAP1 (0.36) | CCNA2CDK2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317949-A | Isoindolines as PMS2 inhibitors | 奈奥芬莱有限公司 | 2024-07-09 | — | — | CN | disclosed |