Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19998979 | 0.78 | NOS3 (0.56) | KDM4EACHERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL25250210 | 0.76 | ACHE (0.40) | KDM4EACHEALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL18320768 | 0.75 | KDM4E (0.40) | KDM4EACHEALDH1A1TSHREEF2K | |
| SCHEMBL19658235 | 0.73 | LMNA (0.47) | KDM4EACHEALDH1A1TSHREEF2K | |
| SCHEMBL25291596 | 0.72 | ACHE (0.40) | KDM4EACHEALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL18320808 | 0.72 | POLB (0.40) | KDM4EACHEALDH1A1HPGDTSHR | |
| SCHEMBL23181388 | 0.70 | GRM2 (0.71) | GRM2 | |
| SCHEMBL25252076 | 0.69 | ACHE (0.40) | ACHESMN1; SMN2L3MBTL1LMNAMEN1 | |
| SCHEMBL25803162 | 0.69 | TSHR (0.38) | KDM4EACHEALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21260230 | 0.67 | GRM2 (0.40) | KDM4EEEF2KLMNAGRM2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140968-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD AND USE THEREFOR | 广州市联瑞制药有限公司 | 2024-07-04 | — | — | WO | disclosed |