Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20604894 | 0.88 | ALDH1A1 (0.42) | PSMD14ALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL1144987 | 0.73 | KDM4E (0.44) | PSMD14ALDH1A1KDM4EKMT2ARXFP1 | |
| SCHEMBL29046616 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4ESMN1; SMN2KMT2APOLB | |
| SCHEMBL1144666 | 0.73 | KDM4E (0.44) | PSMD14ALDH1A1KDM4EKMT2ARXFP1 | |
| SCHEMBL31662269 | 0.73 | TTR (0.43) | SMN1; SMN2KMT2APOLBTSHR | |
| SCHEMBL22939496 | 0.73 | ALDH1A1 (0.41) | PSMD14ALDH1A1KDM4EMAPK10KMT2A | |
| SCHEMBL20604815 | 0.72 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL20604751 | 0.72 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL31662195 | 0.71 | KMT2A (0.43) | ALDH1A1KDM4ESMN1; SMN2KMT2APOLB | |
| SCHEMBL31662290 | 0.69 | USP2 (0.39) | ALDH1A1KDM4ESMN1; SMN2KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |