Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662519 | 0.89 | CA12 (0.41) | USP2NPBWR1ALDH1A1SCN9ASMN1; SMN2 | |
| SCHEMBL31662315 | 0.86 | MAPT (0.41) | USP2NPBWR1ALDH1A1SCN9ASMN1; SMN2 | |
| SCHEMBL31662527 | 0.84 | MAPT (0.41) | USP2NPBWR1ALDH1A1SCN9ASMN1; SMN2 | |
| SCHEMBL31662347 | 0.82 | LMNA (0.38) | USP2ALDH1A1SCN9ALMNAKMT2A | |
| SCHEMBL31662404 | 0.82 | SCN9A (0.40) | USP2NPBWR1ALDH1A1SCN9ALMNA | |
| SCHEMBL31662262 | 0.82 | LMNA (0.46) | USP2SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL31662488 | 0.80 | LMNA (0.37) | USP2NPBWR1SCN9ASMN1; SMN2LMNA | |
| SCHEMBL20604894 | 0.79 | ALDH1A1 (0.42) | USP2ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL31662294 | 0.77 | HAO1 (0.39) | NPBWR1SCN9AKMT2AKDM4E | |
| SCHEMBL31662084 | 0.76 | MAOB (0.36) | USP2HTR2AHTR2CLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |