Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20604894 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2ATSHRPOLBL3MBTL1 | |
| SCHEMBL31662195 | 0.82 | KMT2A (0.43) | MEN1KMT2APOLBL3MBTL1AR | |
| SCHEMBL22939501 | 0.81 | KDM4E (0.42) | TTRTPMTKMT2AALOX15TSHR | |
| SCHEMBL17277747 | 0.81 | TTR (0.43) | TTRTPMTMEN1KMT2AALOX15 | |
| SCHEMBL17875685 | 0.75 | PRNP (0.34) | MEN1KMT2ATSHRHTT | |
| SCHEMBL20610585 | 0.74 | TTR (0.43) | TTRTPMTMEN1KMT2APOLB | |
| SCHEMBL29855960 | 0.74 | TTR (0.43) | TTRTPMTMEN1KMT2APOLB | |
| SCHEMBL30971129 | 0.73 | PSMD14 (0.36) | KMT2ATSHRPOLBSMN1; SMN2 | |
| SCHEMBL16972308 | 0.73 | MEN1 (0.41) | MEN1KMT2AEGLN1SMN1; SMN2MAOB | |
| SCHEMBL31646894 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |