Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971205 | 0.87 | KDM4E (0.35) | PRKCQPRKCDDYRK1ALMNAMAPT | |
| SCHEMBL30971101 | 0.85 | KDM4E (0.33) | DYRK1AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL30971210 | 0.85 | DYRK1A (0.36) | DYRK1AMAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL30971116 | 0.84 | PRMT5 (0.36) | DYRK1AMAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL30971261 | 0.82 | DYRK1A (0.44) | PRKCQPRKCDDYRK1ALMNAMAPT | |
| SCHEMBL30971070 | 0.78 | GRM2 (0.39) | HPGDHSD17B10GAA | |
| SCHEMBL30971218 | 0.77 | KDM4E (0.41) | DYRK1ALMNAMAPTKDM4EHPGD | |
| SCHEMBL30971052 | 0.75 | TUBB4A (0.36) | DYRK1AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL30971088 | 0.71 | ADORA3 (0.41) | MAPTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL30971118 | 0.69 | PIM1 (0.32) | KDM4EALDH1A1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |