Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971101 | 0.90 | KDM4E (0.33) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL30971174 | 0.87 | PRKCQ (0.36) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL30971313 | 0.85 | ATP4A (0.38) | MEN1KMT2AMAPTMAPK1TSHR | |
| SCHEMBL30971335 | 0.80 | GRM2 (0.38) | ALDH1A1 | |
| SCHEMBL30971210 | 0.79 | DYRK1A (0.36) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL30971116 | 0.78 | PRMT5 (0.36) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL30971154 | 0.75 | ATP4A (0.36) | MEN1KMT2AMAPTMAPK1TSHR | |
| SCHEMBL30971218 | 0.73 | KDM4E (0.41) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL30971186 | 0.70 | CTSS (0.33) | KDM4EMEN1KMT2AALDH1A1CTSS | |
| SCHEMBL30971261 | 0.70 | DYRK1A (0.44) | KDM4EHSD17B10MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |