Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BCDIN3D | Q7Z5W3 | 6/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030771 | 1.00 | MEN1 (0.37) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL29786789 | 0.76 | KMT2A (0.40) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL19953294 | 0.76 | KMT2A (0.40) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL30971118 | 0.74 | PIM1 (0.32) | KDM4EALDH1A1PIM1HRH4 | |
| SCHEMBL30971203 | 0.74 | PIM1 (0.34) | PIM1 | |
| SCHEMBL20030772 | 0.72 | BCDIN3D (0.32) | PDE2ATP53BCDIN3D | |
| SCHEMBL30971302 | 0.70 | CYP11B2 (0.32) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL18585253 | 0.69 | MEN1 (0.40) | MEN1KMT2ATP53ABL1PIM1 | |
| SCHEMBL22337069 | 0.68 | CYP11B2 (0.33) | MAPTTP53 | |
| SCHEMBL30971110 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |