Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24597613 | 0.78 | ALDH1A1 (0.33) | MAPTKDM4EMEN1ALDH1A1MAPK1 | |
| SCHEMBL31662367 | 0.77 | KDM1A (0.31) | CYP11B2KDM1A | |
| SCHEMBL21639451 | 0.75 | XDH (0.32) | — | |
| SCHEMBL25386715 | 0.73 | MEN1 (0.33) | MAPTKDM4EMEN1ALDH1A1MAPK1 | |
| SCHEMBL16887703 | 0.70 | TP53 (0.43) | CYP11B2TP53 | |
| SCHEMBL22337069 | 0.70 | CYP11B2 (0.33) | CYP11B2TP53MAPTKDM1A | |
| SCHEMBL25383893 | 0.70 | MEN1 (0.34) | MAPTKDM4EMEN1ALDH1A1MAPK1 | |
| SCHEMBL30971191 | 0.70 | MEN1 (0.37) | TP53ABL1KDRMAPTBCDIN3D | |
| SCHEMBL20030771 | 0.70 | MEN1 (0.37) | TP53ABL1KDRMAPTBCDIN3D | |
| SCHEMBL23357368 | 0.69 | ALDH1A1 (0.41) | TP53MAPTBCDIN3DKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |