Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971260 | 0.91 | LMNA (0.38) | MAPK14MAPK1KDM4ERAB9A | |
| SCHEMBL30971257 | 0.85 | PKMYT1 (0.41) | ARMAPK14PKMYT1 | |
| SCHEMBL27388136 | 0.85 | PKMYT1 (0.41) | ARMAPK14PKMYT1 | |
| SCHEMBL30971229 | 0.82 | AR (0.38) | ARSYKPKMYT1CHEK1CHEK2 | |
| SCHEMBL30971182 | 0.81 | GRM2 (0.41) | PKMYT1 | |
| SCHEMBL30971268 | 0.76 | ACACB (0.38) | ARMAPK14SYKPKMYT1CHEK1 | |
| SCHEMBL30971089 | 0.75 | GRM2 (0.39) | PKMYT1SCN9A | |
| SCHEMBL27402209 | 0.74 | MAPT (0.44) | SYKPKMYT1MKNK1MKNK2HPGDS | |
| SCHEMBL30971197 | 0.73 | SYK (0.36) | ARSYKPKMYT1CHEK1CHEK2 | |
| SCHEMBL30971295 | 0.73 | LMNA (0.38) | MAPK1PLAUNPC1RAB9APLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |