Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971289 | 0.91 | LMNA (0.38) | GLAKMT2APOLBMAPK1GCK | |
| SCHEMBL30971126 | 0.90 | KMT2A (0.43) | GLAKMT2APOLBGCKMAPT | |
| SCHEMBL27388129 | 0.85 | PKMYT1 (0.41) | PKMYT1POLBGCKMAPT | |
| SCHEMBL30971229 | 0.78 | AR (0.38) | SYKPKMYT1MAP3K11KMT2AMAPK1 | |
| SCHEMBL29185091 | 0.75 | SYK (0.41) | SYKSTING1GLAKMT2APOLB | |
| SCHEMBL30971255 | 0.73 | AR (0.38) | SYKPKMYT1MAP3K11MAPK1PLAU | |
| SCHEMBL30971099 | 0.71 | SYK (0.55) | SYKPKMYT1MAPK1 | |
| SCHEMBL30971158 | 0.70 | GRM2 (0.39) | SYKPKMYT1 | |
| SCHEMBL30971070 | 0.70 | GRM2 (0.39) | SYKPKMYT1 | |
| SCHEMBL30971268 | 0.70 | ACACB (0.38) | SYKPKMYT1FLT3MAPK1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |