Sugi Predict

Sugi Predict / Compounds / SCHEMBL3097204

SCHEMBL3097204

SCHEMBL3097204

CCN(C(=O)C(CCc1ccc2ccccc2c1)C(=O)NS(=O)(=O)/C=C/c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.37
▸ UTS2R Q9UKP6 1/20 0.37
▸ GAA P10253 2/20 0.37
▸ HTT P42858 1/20 0.36
▸ PPARG P37231 1/20 0.35
▸ CYP1A2 P05177 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ DUSP3 P51452 2/20 0.34
▸ CDC25B P30305 1/20 0.34
▸ MMP9 P14780 2/20 0.34
▸ HDAC1 Q13547 2/20 0.34
▸ HDAC8 Q9BY41 2/20 0.34
▸ MMP8 P22894 1/20 0.34
▸ MMP1 P03956 1/20 0.34
▸ MMP13 P45452 1/20 0.34
▸ ADAM17 P78536 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3097215 1.00 POLB (0.37) POLBUTS2RGAAHTTPPARG
SCHEMBL3096338 0.89 POLB (0.40) POLBGAAHTTCYP1A2ALDH1A1
SCHEMBL3092948 0.88 GAA (0.38) POLBGAAHTTCYP1A2ALDH1A1
SCHEMBL3079172 0.88 POLB (0.40) POLBGAAHTTCYP1A2ALDH1A1
SCHEMBL3097810 0.88 POLB (0.42) POLBGAAHTTCYP1A2ALDH1A1
SCHEMBL3097822 0.88 POLB (0.42) POLBGAAHTTCYP1A2ALDH1A1
SCHEMBL3079178 0.88 POLB (0.40) POLBGAAHTTCYP1A2ALDH1A1
SCHEMBL3085592 0.88 HTT (0.36) POLBGAAHTTCYP1A2ALDH1A1
SCHEMBL3085590 0.88 HTT (0.36) POLBGAAHTTCYP1A2ALDH1A1
SCHEMBL3097317 0.87 GAA (0.45) POLBGAAPPARGALDH1A1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2172450-B9 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2014-10-08 — — EP disclosed
EP-2172450-B1 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2013-10-16 — — EP disclosed
US-8461209-B2 Malonic acid sulfonamide derivative and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2013-06-11 — — US disclosed
US-20100228026-A1 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-09-09 — — US disclosed
EP-2172450-A1 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2010-04-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100228026-A1 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF REN, AGTR2, AGTR1 POLB 4626/4885UTS2R 23/4885GAA 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.