Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 8/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15030784 | 1.00 | HDAC6 (0.40) | HDAC6MAOAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30963993 | 0.87 | BCHE (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19THPO | |
| SCHEMBL20202064 | 0.87 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15030701 | 0.84 | ADAMTS5 (0.35) | HDAC6ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15030785 | 0.84 | PGR (0.40) | HDAC6ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20202047 | 0.84 | HDAC6 (0.40) | HDAC6MAOAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30963996 | 0.84 | HDAC6 (0.33) | HDAC6MAOAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30964001 | 0.84 | ADAMTS5 (0.31) | HDAC6ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31441077 | 0.84 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL23125658 | 0.83 | MEN1 (0.37) | HDAC6ALDH1A1BCHEGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964635-B | Organic luminescent material based on spiro thioxanthene and preparation method and application thereof | 大连理工大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-117964635-B | Organic luminescent material based on spiro thioxanthene and preparation method and application thereof | 大连理工大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-117964635-A | Organic luminescent material based on spiro thioxanthene and preparation method and application thereof | 大连理工大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964635-A | Organic luminescent material based on spiro thioxanthene and preparation method and application thereof | 大连理工大学 | 2024-05-03 | — | — | CN | disclosed |