Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25085872 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL1445955 | 0.82 | TSHR (0.41) | ALDH1A1HSD17B10TSHRCYP3A4ALOX15 | |
| SCHEMBL2172009 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL1505303 | 0.77 | RAPGEF4 (0.45) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL2933421 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL31090197 | 0.75 | SELL (0.50) | ALDH1A1HSD17B10HPGDCYP3A4ALOX15 | |
| SCHEMBL2654350 | 0.75 | SELL (0.50) | ALDH1A1HSD17B10HPGDCYP3A4ALOX15 | |
| SCHEMBL565244 | 0.75 | TSHR (0.56) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL7724604 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL29768378 | 0.75 | TSHR (0.56) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638438-A1 | ALPHA4 BETA7 INTEGRIN ANTAGONISTS AND USES THEREOF | Xinthera, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024138042-A1 | ALPHA4 BETA7 INTEGRIN ANTAGONISTS AND USES THEREOF | XINTHERA, INC. (US) | 2024-06-27 | — | — | WO | disclosed |