Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091512 | 0.90 | MAPT (0.56) | MAPTMAPK1POLBNPSR1HPGD | |
| SCHEMBL3097190 | 0.81 | ANPEP (0.42) | — | |
| SCHEMBL3097208 | 0.81 | ANPEP (0.42) | — | |
| SCHEMBL3100652 | 0.78 | TSHR (0.35) | MAPTMAPK1TSHRGAAFPR2 | |
| SCHEMBL14064052 | 0.77 | MAPT (0.50) | MAPTMAPK1POLBNPSR1HPGD | |
| SCHEMBL3097313 | 0.76 | TSHR (0.36) | NPSR1TSHRGAAALDH1A1FPR2 | |
| SCHEMBL3098284 | 0.75 | FPR2 (0.52) | MAPTMAPK1GAAFPR2 | |
| SCHEMBL3102568 | 0.74 | FPR2 (0.43) | MAPTMAPK1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL3102486 | 0.74 | FPR2 (0.44) | TSHRGAAALDH1A1FPR2 | |
| SCHEMBL27873367 | 0.71 | ADRA2C (0.53) | MAPTPOLBNPSR1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |