Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.31 |
| ▸ | HTR2A | P28223 | 6/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27171809 | 0.84 | — | — | |
| SCHEMBL25417565 | 0.82 | MAOB (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL30413931 | 0.82 | MAOB (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL30973518 | 0.81 | — | — | |
| SCHEMBL30231635 | 0.79 | PTPN1 (0.31) | — | |
| SCHEMBL30973552 | 0.79 | MAPK1 (0.30) | — | |
| SCHEMBL30994153 | 0.79 | P2RX7 (0.31) | — | |
| SCHEMBL30973428 | 0.78 | — | — | |
| SCHEMBL10157280 | 0.78 | P2RX7 (0.33) | HTR2CHTR2AHTR2B | |
| SCHEMBL25417561 | 0.78 | LPL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |