Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25417561 | 0.79 | LPL (0.33) | — | |
| SCHEMBL30973447 | 0.79 | HTR2C (0.31) | — | |
| SCHEMBL31394265 | 0.78 | LPL (0.35) | MAPK1 | |
| SCHEMBL31394467 | 0.76 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL12533487 | 0.76 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL10157280 | 0.76 | P2RX7 (0.33) | MAPK1 | |
| SCHEMBL30413931 | 0.76 | MAOB (0.40) | — | |
| SCHEMBL25417565 | 0.76 | MAOB (0.40) | — | |
| SCHEMBL15132885 | 0.75 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL25419802 | 0.75 | MAPK1 (0.34) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |