Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584612 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTLMNAMAPK1L3MBTL1 | |
| SCHEMBL1866136 | 0.82 | KMT2A (0.48) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL29831530 | 0.82 | KMT2A (0.48) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL16067896 | 0.82 | NCOA1 (0.47) | SMN1; SMN2NCOA1NCOA3MEN1KMT2A | |
| SCHEMBL16048103 | 0.80 | KMT2A (0.35) | SMN1; SMN2MEN1KMT2AMAPTHPGD | |
| SCHEMBL1919969 | 0.77 | LMNA (0.54) | SMN1; SMN2MAPTLMNAHPGDL3MBTL1 | |
| SCHEMBL29678765 | 0.75 | CYP1A2 (0.38) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL18305182 | 0.75 | CYP1A2 (0.38) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL15068012 | 0.74 | CA12 (0.39) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL25166188 | 0.74 | L3MBTL1 (0.37) | SMN1; SMN2MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |