Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13984211 | 0.89 | ALOX15 (0.53) | LMNACYP1A2AGTR1KDM4EPOLB | |
| SCHEMBL8584612 | 0.84 | SMN1; SMN2 (0.46) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| SCHEMBL13992291 | 0.84 | ALOX15 (0.49) | LMNACYP1A2AGTR1KDM4EPOLB | |
| SCHEMBL9631905 | 0.82 | FFAR1 (0.43) | LMNACYP1A2AGTR1KDM4E | |
| SCHEMBL29679059 | 0.82 | FFAR1 (0.43) | LMNACYP1A2AGTR1KDM4E | |
| SCHEMBL7480447 | 0.82 | KDM4E (0.41) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| SCHEMBL4551683 | 0.81 | KDM4E (0.54) | LMNACYP1A2SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL22069759 | 0.81 | HTR1A (0.53) | L3MBTL1TDP1ALDH1A1APPMAPT | |
| SCHEMBL9338341 | 0.80 | L3MBTL1 (0.56) | CYP1A2KDM4EPOLBL3MBTL1ALOX15 | |
| SCHEMBL14404028 | 0.80 | ALOX15 (0.38) | LMNACYP1A2AGTR1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| CN-101883761-B | New process for the synthesis of moguisteine | A M S A ANONIMA MATERIE SINT E | 2013-03-27 | — | — | CN | disclosed |
| EP-2231627-B1 | NEW PROCESS FOR THE SYNTHESIS OF MOGUISTEINE | A M S A ANONIMA MATERIE SINT E AFFINI S P A (IT) | 2011-06-01 | — | — | EP | disclosed |
| CN-101883761-A | The novel method of the synthesis of moguisteine | A M S A ANONIMA MATERIE SINT E | 2010-11-10 | — | — | CN | disclosed |
| EP-2231627-A2 | NEW PROCESS FOR THE SYNTHESIS OF MOGUISTEINE | A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. (IT) | 2010-09-29 | — | — | EP | disclosed |
| EP-2070915-A1 | New process for the synthesis of moguisteine | A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. (IT) | 2009-06-17 | — | — | EP | disclosed |
| WO-2009071528-A2 | NEW PROCESS FOR THE SYNTHESIS OF MOGUISTEINE | A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.P.A. (IT) | 2009-06-11 | — | — | WO | disclosed |