Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540674 | 0.76 | PTGS2 (0.50) | LMNAPTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL19796297 | 0.74 | NPC1 (0.57) | LMNAPTGS2ALDH1A1MAPTKMT2A | |
| SCHEMBL26424078 | 0.74 | LMNA (0.46) | LMNAPTGS2ALDH1A1HPGDGAA | |
| SCHEMBL750505 | 0.73 | PLAU (0.37) | — | |
| SCHEMBL30698349 | 0.72 | — | — | |
| SCHEMBL28025218 | 0.71 | GLA (0.41) | LMNAALDH1A1HPGDGAAMAPT | |
| SCHEMBL23291609 | 0.71 | LMNA (0.54) | LMNAPTGS2ALDH1A1HPGDGAA | |
| SCHEMBL30599166 | 0.71 | CYP11B2 (0.31) | — | |
| SCHEMBL25397218 | 0.71 | CYP11B2 (0.31) | — | |
| SCHEMBL13116437 | 0.70 | LMNA (0.57) | LMNAPTGS2ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |