SCHEMBL30974030

SCHEMBL30974030

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nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 3/20 0.45
▸ TFPI P10646 1/20 0.44
▸ RAMP3 O60896 5/20 0.43
▸ CALCR P30988 5/20 0.43
▸ OPRL1 P41146 3/20 0.42
▸ OPRM1 P35372 1/20 0.42
▸ OPRD1 P41143 1/20 0.42
▸ OPRK1 P41145 1/20 0.42
▸ KEAP1 Q14145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30974577 0.90 SIRT2 (0.43) IL23RRAMP3CALCR
SCHEMBL31031526 0.87 RAMP3 (0.43) TFPIRAMP3CALCR
SCHEMBL29736243 0.87 PRMT1 (0.46) IL23RTFPIRAMP3CALCROPRL1
SCHEMBL30148948 0.87 NPY4R (0.41) —
SCHEMBL30973989 0.86 OPRM1 (0.57) IL23RTFPIOPRL1OPRM1OPRD1
SCHEMBL29372815 0.86 NPY4R (0.41) —
SCHEMBL29815704 0.85 KEAP1 (0.43) RAMP3CALCRKEAP1
SCHEMBL30069111 0.85 TFPI (0.59) IL23RTFPIRAMP3CALCR
SCHEMBL29987871 0.85 KEAP1 (0.45) IL23RTFPIKEAP1
SCHEMBL31319515 0.84 RAMP3 (0.48) TFPIRAMP3CALCRKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024132726-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 — — WO claimed
WO-2024132725-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF INTRACRANIAL HEMORRHAGIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF INTRACRANIAL HEMORRHAGIC STROKE FROM ACUTE ISCHEMIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 — — WO disclosed
WO-2024132726-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 — — WO disclosed
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