Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 10/20 | 0.41 |
| ▸ | NPY1R | P25929 | 7/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.38 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720811 | 0.96 | MAPK8 (0.44) | KDM1AMAPK8MAPK9MAPK10NPY4R | |
| SCHEMBL8720817 | 0.96 | MAPK8 (0.44) | KDM1AMAPK8MAPK9MAPK10NPY4R | |
| SCHEMBL31097719 | 0.95 | KDM1A (0.47) | KDM1AMAPK8MAPK9MAPK10NPY4R | |
| SCHEMBL31097702 | 0.95 | KDM1A (0.47) | KDM1AMAPK8MAPK9MAPK10NPY4R | |
| SCHEMBL31097677 | 0.95 | KDM1A (0.47) | KDM1AMAPK8MAPK9MAPK10NPY4R | |
| SCHEMBL31239106 | 0.95 | KDM1A (0.47) | KDM1AMAPK8MAPK9MAPK10NPY4R | |
| SCHEMBL30973948 | 0.94 | MEN1 (0.42) | KDM1AMAPK8MAPK9MAPK10MEN1 | |
| SCHEMBL29687469 | 0.93 | MAPK8 (0.48) | KDM1AMAPK8MAPK9MAPK10NPY4R | |
| SCHEMBL29437943 | 0.93 | MAPK8 (0.43) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL29517196 | 0.90 | MEN1 (0.40) | KDM1AMAPK8MAPK9MAPK10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |