SCHEMBL30975971

SCHEMBL30975971

CCOC(=O)c1c(C(F)(F)F)c(C2CC2)nn1CC12CC1CC(F)(F)C2

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLAT P00750 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27417403 0.88 ALDH1A1 (0.32) ALDH1A1TSHRGAAHTTHSD17B10
SCHEMBL30975878 0.86 ALDH1A1 (0.32) ALDH1A1TSHRGAAHTTHSD17B10
SCHEMBL30975816 0.86
SCHEMBL30975835 0.85 CNR2 (0.30)
SCHEMBL27417593 0.84 KMT2A (0.33) PLATALDH1A1TSHRGAAHTT
SCHEMBL30976004 0.84 ALDH1A1 (0.33) PLATALDH1A1TSHRGAAHTT
SCHEMBL30975872 0.82 KMT2A (0.32) PLATALDH1A1TSHRGAAHTT
SCHEMBL24906236 0.81 LMNA (0.34) PLATALDH1A1TSHRGAAHTT
SCHEMBL30976017 0.80 ALDH1A1 (0.32) PLATALDH1A1TSHRGAAHTT
SCHEMBL30976018 0.80 ALDH1A1 (0.32) PLATALDH1A1TSHRGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634159-A1 SULFOXIMINES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-10-22 EP disclosed
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 WO disclosed