SCHEMBL30976256

SCHEMBL30976256

Cn1nc(C(=O)N2CCN(c3cnn(-c4ccccc4)c(=O)c3Cl)CC2)c2ccccc2c1=O

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DCTPP1 Q9H773 4/20 0.63
ALDH1A1 P00352 11/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
RXFP1 Q9HBX9 1/20 0.59
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPT P10636 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
KDM4E B2RXH2 1/20 0.54
PKM P14618 1/20 0.54
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30976255 0.88 ALDH1A1 (0.61) DCTPP1ALDH1A1SMN1; SMN2RXFP1MAPT
SCHEMBL11943534 0.78 ALDH1A1 (0.73) DCTPP1ALDH1A1SMN1; SMN2RXFP1KMT2A
SCHEMBL30976378 0.74 KMT2A (0.58) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL30976402 0.74 KMT2A (0.58) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL13219330 0.74 ALDH1A1 (0.70) DCTPP1ALDH1A1SMN1; SMN2RXFP1KMT2A
SCHEMBL30976266 0.73 MEN1 (0.56) ALDH1A1MEN1KMT2AMAPTNPSR1
SCHEMBL4670530 0.72 DCTPP1 (0.65) DCTPP1ALDH1A1SMN1; SMN2RXFP1MEN1
SCHEMBL30976507 0.72 MEN1 (0.64) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL30976438 0.72 MEN1 (0.57) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL4672611 0.71 DCTPP1 (0.64) DCTPP1ALDH1A1SMN1; SMN2RXFP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619387-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2025-09-24 EP disclosed
WO-2024108131-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed