SCHEMBL30976255

SCHEMBL30976255

CCn1nc(C(=O)N2CCN(c3cnn(-c4ccccc4)c(=O)c3Cl)CC2)c2ccccc2c1=O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.61
DCTPP1 Q9H773 4/20 0.61
RXFP1 Q9HBX9 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.59
MAPT P10636 3/20 0.56
KDM4E B2RXH2 3/20 0.52
GAA P10253 1/20 0.52
HTT P42858 1/20 0.52
PKM P14618 1/20 0.51
LMNA P02545 2/20 0.51
TSHR P16473 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30976256 0.88 DCTPP1 (0.63) ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT
SCHEMBL11943534 0.73 ALDH1A1 (0.73) ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT
SCHEMBL30976411 0.73 TP53 (0.56) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL30976318 0.73 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2MAPTKDM4EGAA
SCHEMBL30976354 0.72 ALDH1A1 (0.58) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL31199177 0.72 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MAPTKDM4EGAA
SCHEMBL30976451 0.72 L3MBTL1 (0.56) ALDH1A1SMN1; SMN2MAPTKDM4EGAA
SCHEMBL13219330 0.72 ALDH1A1 (0.70) ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT
SCHEMBL30976372 0.71 KMT2A (0.56) ALDH1A1SMN1; SMN2MAPTKDM4EHTT
SCHEMBL30976298 0.71 KDM4E (0.49) ALDH1A1MAPTKDM4EGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619387-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2025-09-24 EP disclosed
WO-2024108131-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed