SCHEMBL30976568

SCHEMBL30976568

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)CN)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 3/20 0.48
▸ PRSS1 P07477 1/20 0.47
▸ TFPI P10646 1/20 0.47
▸ RXFP1 Q9HBX9 1/20 0.45
▸ NPY4R P50391 14/20 0.45
▸ NPY5R Q15761 9/20 0.45
▸ NPY1R P25929 9/20 0.45
▸ NPY2R P49146 6/20 0.45
▸ PCSK6 P29122 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29886744 0.92 TFPI (0.48) FURINPRSS1TFPIRXFP1NPY4R
SCHEMBL30881182 0.92 TFPI (0.46) FURINTFPINPY4RNPY5RNPY1R
SCHEMBL30543180 0.89 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2R
SCHEMBL30371101 0.89 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2R
SCHEMBL6850341 0.89 FURIN (0.40) FURINPRSS1TFPINPY4RNPY5R
SCHEMBL6850333 0.89 FURIN (0.40) FURINPRSS1TFPINPY4RNPY5R
SCHEMBL31670624 0.88 TFPI (0.49) FURINPRSS1TFPIRXFP1NPY4R
SCHEMBL29531521 0.88 TFPI (0.45) FURINPRSS1TFPIRXFP1NPY4R
SCHEMBL29435094 0.88 SLC15A2 (0.45) NPY4RNPY5RNPY1RNPY2R
SCHEMBL30148473 0.88 FURIN (0.46) FURINPRSS1TFPIRXFP1NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2026-04-02 — — US disclosed
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2025-12-18 — — US disclosed
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-07-31 — — US disclosed
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-07-29 — — US disclosed
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-04-24 — — US disclosed
US-20240269269-A1 Self-Assembling Nanoparticles VACCITECH NORTH AMERICA, INC. (US) 2024-08-15 — — US disclosed
CN-118103059-A Self-assembled nanoparticles based on amphiphilic peptides 巴林萨斯生物疗法北美公司 2024-05-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides IAPP, BRCA1, ANXA11 FURIN 226/4885PRSS1 732/4885TFPI 4467/4885
US-20240269269-A1 Self-Assembling Nanoparticles UBE2B, CD4, UBE2G2 FURIN 320/4885PRSS1 1876/4885TFPI 3586/4885
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER IL2, IFNG, ICOS FURIN 2348/4885PRSS1 757/4885TFPI 185/4885
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES UBE2B, CD4, HRH1 FURIN 327/4885PRSS1 1873/4885TFPI 3551/4885
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES VIP, HM13, SPPL2B FURIN 6/4885PRSS1 1548/4885TFPI 1210/4885
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response MYD88, ICOS, CD4 FURIN 16/4885PRSS1 814/4885TFPI 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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