SCHEMBL30881182

SCHEMBL30881182

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)CN)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.46
▸ QRFPR Q96P65 1/20 0.44
▸ NPY4R P50391 9/20 0.44
▸ NPY5R Q15761 8/20 0.44
▸ NPY1R P25929 7/20 0.44
▸ NPY2R P49146 5/20 0.44
▸ CTSB P07858 1/20 0.42
▸ FURIN P09958 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30881179 0.94 NPY4R (0.46) TFPINPY4RNPY5RNPY1RNPY2R
SCHEMBL29886742 0.93 QRFPR (0.45) TFPIQRFPRCTSBFURIN
SCHEMBL30976568 0.92 FURIN (0.48) TFPINPY4RNPY5RNPY1RNPY2R
SCHEMBL29886744 0.91 TFPI (0.48) TFPINPY4RNPY5RNPY1RNPY2R
SCHEMBL30826350 0.90 NPY4R (0.47) TFPIQRFPRNPY4RNPY5RNPY1R
SCHEMBL31665959 0.90 NMT2 (0.41) TFPIQRFPRNPY4RNPY5RNPY1R
SCHEMBL31665989 0.90 TFPI (0.49) TFPINPY4RNPY5RNPY1RNPY2R
SCHEMBL30543180 0.88 NPY4R (0.52) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL6850341 0.88 FURIN (0.40) TFPIQRFPRNPY4RNPY5RNPY1R
SCHEMBL6850333 0.88 FURIN (0.40) TFPIQRFPRNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2026-04-02 — — US disclosed
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2025-12-18 — — US disclosed
EP-4608455-A1 SELF-ASSEMBLING NANOPARTICLES Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 — — EP disclosed
EP-4608437-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 — — EP disclosed
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-07-31 — — US disclosed
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-07-29 — — US disclosed
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-04-24 — — US disclosed
US-20240269269-A1 Self-Assembling Nanoparticles VACCITECH NORTH AMERICA, INC. (US) 2024-08-15 — — US disclosed
CN-118103059-A Self-assembled nanoparticles based on amphiphilic peptides 巴林萨斯生物疗法北美公司 2024-05-28 — — CN disclosed
WO-2024092028-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER VACCITECH NORTH AMERICA, INC. (US) 2024-05-02 — — WO disclosed
WO-2024092030-A1 SELF-ASSEMBLING NANOPARTICLES VACCITECH NORTH AMERICA, INC. (US) 2024-05-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides IAPP, BRCA1, ANXA11 TFPI 4467/4885QRFPR 2223/4885NPY4R 2700/4885
US-20240269269-A1 Self-Assembling Nanoparticles UBE2B, CD4, UBE2G2 TFPI 3586/4885QRFPR 1479/4885NPY4R 2033/4885
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER IL2, IFNG, ICOS TFPI 185/4885QRFPR 2424/4885NPY4R 669/4885
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES UBE2B, CD4, HRH1 TFPI 3551/4885QRFPR 1505/4885NPY4R 2014/4885
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES VIP, HM13, SPPL2B TFPI 1210/4885QRFPR 73/4885NPY4R 1087/4885
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response MYD88, ICOS, CD4 TFPI 2280/4885QRFPR 179/4885NPY4R 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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