Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.43 |
| ▸ | CTSK | P43235 | 14/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976911 | 0.84 | USP8 (0.39) | CTSSCTSKNSD2 | |
| SCHEMBL30976826 | 0.84 | ADORA2A (0.36) | CTSSCTSKNSD2 | |
| SCHEMBL30976918 | 0.82 | CTSS (0.34) | CTSSCTSKNSD2 | |
| SCHEMBL30976919 | 0.82 | CTSS (0.36) | CTSSCTSKNSD2 | |
| SCHEMBL30976858 | 0.82 | CTSS (0.36) | CTSSCTSK | |
| SCHEMBL30976952 | 0.81 | CTSS (0.36) | CTSSCTSK | |
| SCHEMBL30976904 | 0.80 | CTSS (0.45) | CTSSCTSK | |
| SCHEMBL30976849 | 0.80 | CTSS (0.35) | CTSSCTSK | |
| SCHEMBL30976872 | 0.80 | DDB1 (0.35) | CTSSCTSK | |
| SCHEMBL27249457 | 0.70 | NR1H2 (0.44) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140679-A1 | SPIROCYCLIC HPK1 ANTAGONISTS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-07-04 | — | — | WO | disclosed |