Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.34 |
| ▸ | FEN1 | P39748 | 4/20 | 0.34 |
| ▸ | CTSS | P25774 | 6/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | USP8 | P40818 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976911 | 0.84 | USP8 (0.39) | CTSSCTSKCYP17A1USP8 | |
| SCHEMBL30976826 | 0.83 | ADORA2A (0.36) | CTSSCTSKCYP17A1USP8 | |
| SCHEMBL30976904 | 0.81 | CTSS (0.45) | CTSSCTSKUSP8 | |
| SCHEMBL30976919 | 0.81 | CTSS (0.36) | CTSSCTSKUSP8 | |
| SCHEMBL30976918 | 0.81 | CTSS (0.34) | CTSSCTSKCYP17A1IKBKBUSP8 | |
| SCHEMBL30976858 | 0.81 | CTSS (0.36) | CTSSCTSKCYP17A1USP8 | |
| SCHEMBL30976869 | 0.80 | CTSS (0.43) | CTSSCTSK | |
| SCHEMBL30976849 | 0.79 | CTSS (0.35) | CTSSCTSKUSP8 | |
| SCHEMBL30976952 | 0.78 | CTSS (0.36) | CTSSCTSKMBOAT4 | |
| SCHEMBL30206278 | 0.66 | DDB1 (0.37) | DDB1CRBNFLT3CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140679-A1 | SPIROCYCLIC HPK1 ANTAGONISTS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-07-04 | — | — | WO | disclosed |