Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.36 |
| ▸ | CTSK | P43235 | 13/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976849 | 0.93 | CTSS (0.35) | CTSSCTSK | |
| SCHEMBL30976919 | 0.89 | CTSS (0.36) | CTSSCTSK | |
| SCHEMBL30976904 | 0.87 | CTSS (0.45) | CTSSCTSK | |
| SCHEMBL30976911 | 0.83 | USP8 (0.39) | CTSSCTSK | |
| SCHEMBL30976918 | 0.82 | CTSS (0.34) | CTSSCTSK | |
| SCHEMBL30976826 | 0.82 | ADORA2A (0.36) | CTSSCTSK | |
| SCHEMBL30976869 | 0.81 | CTSS (0.43) | CTSSCTSK | |
| SCHEMBL30976858 | 0.80 | CTSS (0.36) | CTSSCTSK | |
| SCHEMBL30976872 | 0.78 | DDB1 (0.35) | CTSSCTSKMBOAT4 | |
| SCHEMBL31159907 | 0.72 | GAA (0.40) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140679-A1 | SPIROCYCLIC HPK1 ANTAGONISTS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-07-04 | — | — | WO | disclosed |