Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30977200 | 1.00 | RORC (0.38) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL25240441 | 1.00 | RORC (0.38) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL30977168 | 1.00 | RORC (0.38) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL25244104 | 0.93 | ABCB1 (0.39) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL25209900 | 0.91 | KDM1A (0.36) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL30089167 | 0.91 | KDM1A (0.36) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL25206779 | 0.90 | GPR119 (0.34) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL30088961 | 0.90 | CCR5 (0.35) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL30392576 | 0.90 | GPR119 (0.34) | RORCGPR119KDM4EPKMKDM1A | |
| SCHEMBL30977161 | 0.89 | KDM1A (0.35) | RORCGPR119KDM4EPKMKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131827-A1 | KRAS G12D INHIBITORS AND USES THEREOF | 上海和誉生物医药科技有限公司 | 2024-06-27 | — | — | WO | disclosed |