Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30977412 | 0.82 | RXRA (0.36) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL18338474 | 0.79 | DRD2 (0.45) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL30175354 | 0.78 | DRD2 (0.43) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL25421011 | 0.75 | DRD2 (0.45) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL25061842 | 0.74 | SCN5A (0.43) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL29786198 | 0.72 | ACACB (0.38) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL30496653 | 0.71 | DRD2 (0.43) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL24567001 | 0.71 | DRD2 (0.54) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL25416514 | 0.70 | KDR (0.47) | BMPR1BACVR1BACVRL1ACVR1ALDH1A3 | |
| SCHEMBL4968862 | 0.70 | DRD2 (0.34) | DRD2DRD4DRD3DRD1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619402-A1 | GPR17 MODULATORS AND USES THEREOF | Myrobalan Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-119613397-A | N-heteroaromatic ring-3-sulfonamide compounds and use thereof for preparing GPR17 receptor inhibitors | 迈巴制药(南京)有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024104462-A1 | GPR17 MODULATORS AND USES THEREOF | MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) | 2024-05-23 | — | — | WO | disclosed |